[2015/01/13]Dr. You-Yin Chen and His Team Win the 11th National Innovation Award
Dr. You-Yin Chen and His Team Win the 11th National Innovation Award
The "Neural Probe Chip" joint R&D team, led by Dr. You-Yin Chen (Department of Biomedical Engineering, NYMU) and Dr. San-Yuan Chen (Department of Materials Science and Engineering, NCTU), has successfully integrated industry demand and research achievements and scored a glorious triumph by being awarded the 11th National Innovation Award in the Academic Research Category by Institute for Biotechnology and Medicine Industry, Taiwan (2014). This award is the highest honor given to domestic biomedical engineering industries and academic research units in terms of innovative inventions. Chens' team winning this award provides solid proof of NYMU's superb capability in bioelectronic and biomaterial engineering.
Here, Chens' team developed the novel combination of functional nanocarriers and nano-manufacturing technology to produce three-dimensional nanocarrier-based interfaces that support long-term neural implantation. Chens' team synthesized amphiphilically modified polysaccharide nanogels (PMSC), which demonstrate physical and chemical properties that mimic brain tissue and possess anti-biofouling ability. Finally, they directly printed OPMSC on the insulation surface of a micro-scaled polyimide-based nerual probe. The implanted neural probe showed relatively lower impedance and a higher signal quality than the non-coated probe in vivo implantation chronically. Through magnetic resonance imaging and immunostaining, the OPMCS-coated probe alleviated edema at the acute phase, and further reduced tissue trauma at the chronic phase , which has becoming one of the leading research tools to study brain function and is playing a pivotal role in the US NIH BRAIN Initiative as well as other major brain mapping projects worldwide.
Dr. You-Yin Chen(right 2) and His Team Win the 11th National Innovation Award